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METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE

About

DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE used to control nausea and vomiting during pregnancy. It helps treat morning sickness (nauseous feeling during the first trimester) in pregnant women. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the body's natural response to discharge the stomach content forcefully.

DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE contains Methylcobalamin, L Methylfolate Calcium, Pyridoxal 5 Phosphate (vitamin B6) and Doxylamine Succinate. Methylcobalamin and L Methylfolate Calcium can provide essential nutrients during pregnancy. Doxylamine succinate belongs to the class of antihistamines that work by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine/vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxal-5-phosphate works by increasing the level of vitamin B6 in the body. Thus, it helps treat nausea and vomiting during pregnancy.

Take DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE as prescribed. You are advised to take DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as drowsiness, constipation, dizziness, or blurred vision. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you are allergic to any foods or medicines, please tell your doctor. The DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE is usually not taken by breastfeeding mothers as it passes into breast milk. DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE should not be given to children as safety and efficacy have not been established. DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE may cause dizziness; therefore, drive with caution. Avoid consuming alcohol along with DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE as it could lead to increased dizziness. If you are taking MAO inhibitors, inform your doctor, as taking them along with DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE may cause unpleasant side effects.

Uses of METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE

Treatment of nausea and vomiting in pregnancy

Medicinal Benefits

DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE combines four drugs: Methylcobalamin, L-methyl folate calcium, pyridoxal 5 phosphate (vitamin B6), and doxylamine succinate. DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE relieves nausea and vomiting that occurs in pregnancy due to some hormonal changes. It acts by blocking the activity of some chemicals which make you sick. It will also increase your vitality during pregnancy.

Directions for Use

Swallow it as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE

  • Drowsiness
  • Dizziness
  • Blurred vision
  • Constipation

In-Depth Precautions and Warning

Drug Warnings

Do not take DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE if you are allergic to any of its contents. Tell your doctor if you have asthma, increased eye pressure, narrow-angle glaucoma, stomach ulcer, a blockage in your gut (digestive tract), or liver or kidney problems. Inform your doctor if you are taking medicines for depression, cough or cold medicines, sleeping medicines, or certain pain medicines. DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE should not be taken by breastfeeding mothers as it passes into breast milk. DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE as it could lead to increased dizziness.

Drug Interactions

Drug-Drug Interactions: DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE may interact with other antihistamine drugs (e.g. diphenhydramine, chlorpheniramine), anti-anxiety medications (e.g. alprazolam, chlordiazepoxide), monoamine oxidase inhibitors (e.g. selegiline, isocarboxazid), and sedative-hypnotics (lorazepam).
Drug-Food Interactions: You are recommended to avoid alcohol consumption while taking DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE since it could lead to increased dizziness and drowsiness.
Drug-Disease Interactions: DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE should be cautiously used in patients with depression, asthma/COPD, heart problems, severe liver or kidney diseases, glaucoma, and malabsorption syndrome.

Drug-Drug Interactions Checker List:

  • DIPHENHYDRAMINE
  • CHLORPHENIRAMINE
  • ALPRAZOLAM
  • CHLORDIAZEPOXIDE
  • SELEGILINE
  • ISOCARBOXAZID
  • LORAZEPAM
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended to avoid alcohol consumption while taking DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE since it could lead to increased dizziness and drowsiness.

    • Safety Warning

      Pregnancy

      safe

      DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE is intended for use in pregnant women. However, please consult your doctor if you have any concerns.

    • Safety Warning

      Breast Feeding

      safe if prescribed

      Limited data is available. It is safe to take DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE in breastfeeding if prescribed by a doctor.

    • Safety Warning

      Driving

      caution

      DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE may cause dizziness, drowsiness, and blurred vision; hence, do not drive or operate heavy machinery if you feel dizzy.

    • Safety Warning

      Liver

      consult your doctor

      Limited information is available about using DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE in patients with liver disease. If you have liver problems, inform your doctor before taking DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE.

    • Safety Warning

      Kidney

      consult your doctor

      Limited information is available about using DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE in patients with kidney disease. If you have kidney problems, inform your doctor before taking DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE.

    • Safety Warning

      Children

      unsafe

      DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE is not recommended for children below 18 years of age, as the safety and efficacy have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Limit taking foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 
    • Do not have large meals at a time; instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
    • Practice yoga and recreation techniques to manage your emotional stress.
    • If you are lactose intolerant, avoid using dairy products since it can worsen your stomach discomfort.
    • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
    • Drink plenty of fluids to prevent dehydration.
    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

    Patients Concern

    Disease/Condition Glossary

    Morning sickness: It is a common symptom during pregnancy that usually happens within the first trimester (first three months) of pregnancy, but some pregnant women have it throughout pregnancy. In some cases, pregnant women experience excessive nausea and vomiting that progresses to a condition called hyperemesis gravidarum. It causes electrolyte imbalance and weight loss in pregnant women. The most common cause of morning sickness is increased hormone levels during the first weeks of pregnancy.

    Nausea: It is an uneasy feeling in the stomach that may come and go in waves in which a person feels a strong urge to vomit. It happens before vomiting.

    Vomiting: It is a natural response of the body in which a person expels stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain or irritation to the stomach.

    FAQs

    DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE is used to treat nausea and vomiting in pregnancy.

    DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE contains methylcobalamin, L-methyl folate calcium, pyridoxal 5 phosphate (vitamin B6), and doxylamine succinate. Methylcobalamin and L Methylfolate Calcium can provide essential nutrients during pregnancy. Doxylamine succinate works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxal-5-phosphate works by increasing the level of vitamin B6 in the body and treating nausea and vomiting during pregnancy.

    Never increase your prescribed dose. If you have taken an overdose of this medicine accidentally, seek emergency medical help.

    DOXYLAMINE SUCCINATE+L METHYLFOLATE CALCIUM+METHYLCOBALAMIN+PYRIDOXAL 5 PHOSPHATE may cause constipation as one of its side effects. You can avoid it by including high-fibre food in your diet that helps improve digestion. Limit the intake of alcohol to manage your constipation.

    Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.

    Available Medicines for

    METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE

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